When we talk about cannabinoids we always think of cannabidiol (CBD) and tetrahydrocannabinol (THC) but the truth is that the hemp plant is a complex plant. We can get more than a hundred types of cannabinoids, and so far science has managed to recognize and to study CBD and THC in depth, but thanks to scientific research, other medicinal benefits of this plant come to light. Although we have seen more information on 2 of its important cannabinoids CBD and THC, currently 2 more are being studied separately, Cannabigerol (CBG) and Cannabinol (CBN). Although work is still being carried out in laboratories to achieve the extraction and use of each of these cannabinoids individually, it is quite difficult to find them on the market, in this way we can obtain benefits from their properties together through essential oils such as those that we offer at www.integrityhempceuticals.com there is a variety of flavors such as mint, vanilla, lemon, etc.
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CBG is a non-psychoactive cannabinoid that can help treat multiple conditions, illnesses, and ailments. Although THC and CBD are two commonly consumed cannabinoids, CBG is gaining more popularity and attention due to its medicinal value.
WHAT IS CANNABIGEROL (CBG)?
CBG is a non-psychoactive cannabinoid, it is one of more than 100 known cannabinoids. In fact, it is the first to appear in the plant and, therefore, the rest of cannabinoids are derived from it. Among others, THC, CBD, CBG and Cannabinol or (CBN), which we will talk about later. And this is because initially, these substances begin as derivatives of cannabigerolic acid (CBGA), which once exposed to heat, is modified, deacidified and generates CBG, THC and CBD, among many other cannabinoids. Studies have revealed that the CB1 receptors of the endocannabinoid system are activated by cannabigerol, thus affecting the central nervous system. In particular, through the application of heat either through photosynthesis or through decarboxylation, CBG will go from its acidic form to its active form and will be ready for use. Although normally the second method is the most used since it requires less time.
BENEFITS OF CBG
• It is antibacterial and antifungal
• May inhibit the growth of cancer cells
• Alleviate the pain
• It is anti-inflammatory
• Promotes bone growth
• It helps to sleep
• It is useful in the treatment of anorexia and cachexia
• Improves intestinal diseases
• It is antidepressant
• Glaucoma:
This is because CBG works as a vasodilator, helps to drain fluid from the eyes, and also relieves pressure in the eye.
• Inflammatory bowel diseases:
CBG was found to have anti-inflammatory properties, specifically targeting the areas where pain originates.
• Antibacterial:
There are studies that indicate that cannabigerol is very effective as an antibacterial and antifungal, after being administered topically to treat skin diseases and infections.
• Huntington's disease:
Huntington's disease is a brain disease characterized by progressive neurodegeneration, the role of CBG in this case has been to act as a neuroprotective and antidepressant. This would do well either in combination with other phytocannabinoids or independently.
CBG inhibits the activity of the neutotransmitter GABA in the brain, reducing anxiety and muscle tension. • Psoriasis: Psoriasis is a disease of the immune system, which usually presents a skin rash, scaling, itching and sometimes burning, although it can have different symptoms depending on the area of the body and the causes that originate it, such as allergies or stress. • Cancer: CBG works significantly by reducing the formation of cancer cells in different parts of the body, such as the skin, colon, breasts, prostate and other types of cancer.
WHAT IS CANNABINOL (CBN)?
Although we mentioned that CBN is one of the more than one hundred cannabinoids that we find in the Cannabis sativa plant, it is necessary to clarify this definition a little more. Especially if we take into account that this compound is produced by heating or oxidation of THC. The truth is that CBN is very interesting from a therapeutic point of view. Especially thanks to its beneficial effects against insomnia. As well as other therapeutic functions that it shares with CBD that we will talk about later. First of all, unlike other cannabinoids such as CBD or THC, CBN is not found naturally in cannabis plants, it is a substance that is formed from the degradation of THC, either through oxidation or by the application of heat. That is why the greater the a
mount of THC, the greater the amount of CBN we will have.
HOW IS CBN OBTAINED?
The oxidation or aging of the plant: it is a slower process that takes place once we have collected the cannabis. In this way, by the action of heat or oxygen, THC is degraded and CBN is obtained. It is the most common method to get this compound.
Finally, since the indica varieties of Cannabis sativa contain the most THC, they are also the most recommended if what we are looking for is to obtain a greater amount of cannabinol
It is true that CBN has sedative properties that could make us think that it has a certain psychoactive effect. However, unlike THC, CBN does not produce changes in our mental state.
CBN is the result of a chemical process. THCA loses its hydrogen molecules, so it is converted to CBNA. When it is subjected to a lot of heat or sun exposure, it becomes CBN. This occurs most often in the indica variety of cannabis.
Once it is clear what CBN is, it is possible to determine the immense properties that this component generates for health. The most recognized effect is the sedative, for which CBN is assigned as a great ally for people who suffer insomnia and anxiety attacks as a result of it.
BENEFITS OF CBN
According to a 2005 study published in the Journal of Neuroimmunology, CBN can have a strong anti-inflammatory effect, by moderating inflammation by targeting the immune system. It is also hypothesized that CBN is an appetite stimulant. This study was conducted with CBD and CBN in rats. The researchers found that CBN increased the amou
nt of food eaten by the rats and the total time they spent eating.
• Insomnia (Insomnia)
Scientific consensus has determined that the fight against insomnia is the best and most well-known property that CBN has, it promotes sleep. This is because CBN is a powerful sedative. Also, the sedative power of CBN allows to control the collateral effects of insomnia, especially anxiety attacks.
• Analgesic - Anti-inflammatory- Antiemetic:
It is useful for treating pain, nausea and vomiting
CBN in this sense is quite similar to the cannabinoid CBD, because it has analgesic and antibacterial properties and in addition to the fact that it can also act as an anti-inflammatory. CBN stimulates the release of peptides towards the nerves, so that in this way the sensation of pain could decrease after consumption. This could help in different circumstances such as sports injuries or even burns.
• Glaucoma:
It lowers intraocular pressure, which makes it a useful treatment for glaucoma, conditions like glaucoma require rapid treatment to slow its growth, and CBN is fully capable of contributing to this process.
• Psoriasis:
It is useful for the treatment of psoriasis. CBN contributes to the reduction of psoriasis, because it reduces the growth of skin cells called keratinocytes.
• Strengthens bone regeneration:
The healing of broken bones is a painful, tedious and long process that you could find in the CBN a stimulator and accelerator. This cannabinoid would be able to recruit mesenchymal stem cells into the bone marrow. CBN produces an increase in fibroblast cells, which directly affects bone healing. This results in tissues recovered in less time.
• Anticonvulsant properties:
One of the first medicinal uses found for the components of cannabis was as an anticonvulsant. Although to a lesser extent than CBD and THC, scientific studies have determined that CBN also has these anticonvulsant properties. In this way, millions of patients with diseases such as epilepsy have been able to improve their quality of life thanks to cannabinoids.
The CBN is among them.
What can you expect from CBG and CBN in the future?
Well, that the studies in the next strains of seeds and varieties of marijuana can obtain higher levels of these cannabinoids so that the research process can be simpler and allows to get more out of it from a medicinal and therapeutic point of view. It is important to highlight the fact that, thanks to their properties mentioned throughout this article, these components can help many people who even today cannot solve their health problems with regular drugs, so they would represent an alternative natural and innovative that would surely provide better results. Sources
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